Wissenschaftliche Tätigkeit/Publikationen

"Zweierlei gibt es, Wissenschaft und Einbildung, erstere führt zum Wissen, letztere zum Nichtwissen.“
Hippokrates von Kos (460 bis 377 v. Chr.)

Diesen Leitspruch folgend widmet sich unsere Klinik unter der Leitung von a.o. Univ.-Prof. Dr. Lukas J. Motloch, MSc, PhD in enger Kooperation mit dem Kepler Universitätsklinikum Linz und der Paracelsus Medizinischen Universität Salzburg der wissenschaftlichen Erforschung von kardiovaskulären Krankheitsbildern.

Zu diesem Zweck werden in Kooperation mit klinisch und grundlagenwissenschaftlich tätigen Kollegen/innen in einem multidisziplinären Team, standortübergreifend die Ursachen sowie neue Therapieansätze von diversen kardiovaskulären Krankheitsbildern untersucht. Hierbei liegt unser Schwerpunkt in der Erforschung von kardialen Arrhythmien, der Herzinsuffizienz oder anderen Formen von Kardiomyopathie, welche eine der häufigsten Todesursachen weltweit darstellen. Ein weiterer Schwerpunkt besteht in der Untersuchung von kardiovaskulären Pathologien, welche mit der COVID-19 Erkrankung assoziiert sind.

Weitere nationale und internationale Kooperationen bestehen hierbei mit der naturwissenschaftlichen Universität Salzburg, dem Landesklinikum Wiener Neustadt sowie der Klinik für Kardiologie, Kliniken Maria Hilf, Mönchengladbach, Deutschland und der Klinik für Kardiologie I, Universitätsklinikum Münster, Deutschland.

Angebote für wissenschaftlich interessierte MitarbeiterInnen und Studierende

1. Studierende:

Unter der Anleitung von Prof. Lukas J. Motloch besteht für Studierende der Medizinischen Fakultät der Johannes Kepler Universität Linz die Möglichkeit Ihre Bachelorarbeit an unserer Abteilung zu absolvieren. Hierbei kann das Thema nach individueller Absprache gewählt werden.

2. Wissenschaftlich interessierte Mitarbeiter/-innen:

In Kooperation mit der Paracelsus Medizinischen Universität Salzburg können unsere Ärztinnen/Ärzte unter der Betreuung von Prof. Lukas J. Motloch im Rahmen des Studienganges DOCTORAL PROGRAMME IN MEDICAL SCIENCE (PH.D.) berufsbegleitend das medizinisch-wissenschaftliche Arbeiten erlernen. Hierbei kann das Thema nach individueller Absprache gewählt werden.

Wird der PhD-Titel innerhalb des Zeitraums der Ausbildung zum Facharzt absolviert, besteht die Möglichkeit diese Tätigkeit von der Landesärztekammer als wissenschaftliches Ausbildungsmodul anerkennen zu lassen. In diesem Falle verkürzt sich die Ausbildungszeit in der Sonderfach-Schwerpunktausbildung um neun Monate.

Bei Interesse oder Fragen freuen wir uns über eine Kontaktaufnahme:

a.o. Univ.-Prof. Dr. Lukas J. Motloch, MSc, PhD

Email: lukas.motloch@ooeg.at

Sekretariat:

Frau Mag.a Sonja Neulinger

Tel.: 05 055471-24401
E-Mail: sonja.neulinger@ooeg.at

Publikationen

• Paar V, Haslinger M, Krombholz-Reindl P, Pittner S, Neuner M, Jirak P, Kolbitsch T, Minnich B, Schroedl F, Kaser-Eichberger A, Kopp K, Koller A, Steinwender C, Lichtenauer M, Monticelli FC, Seitelberger R, Hoppe UC, Dinges C, Motloch LJ
  Hypertrophic cardiomyopathy is characterized by alterations of the mitochondrial calcium uniporter complex proteins: insights from patients with aortic valve stenosis versus hypertrophic obstructive cardiomyopathy
  Front. Pharmacol., 22 November 2023;14. doi: https://doi.org/10.3389/fphar.2023.1264216

• Kopp K, Motloch L, Berezin A, Maringgele V, Ostapenko H, Mirna M, Schmutzler L, Dieplinger A, Hoppe
  Missed Opportunities in Implementation and Optimization of Lipid-Lowering Therapies in Very-High-Risk Patients Presenting with ST-Segment Elevation Myocardial Infarction.
  J Clin Med. 2023 Aug 31;12(17):5685. doi: 10.3390/jcm12175685.

• Fiedler L, Motloch LJ, Dieplinger AM, Jirak P, Davtyan P, Gareeva D, Badykova E, Badykov M, Lakman I, Agapitov A, Sadikova L, Pavlov V, Föttinger F, Mirna M, Kopp K, Hoppe UC, Pistulli R, Cai B, Yang B, Zagidullin N
  Early antithrombotic post-discharge therapy using prophylactic DOAC or dipyridamole improves long-term survival and cardiovascular outcomes in hospitalized COVID-19 survivors.
  Front Pharmacol. 2023 14:1093396. DOI: 10.3389/fphar.2023.1093396.

• Ohnewein B, Shomanova Z, Paar V, Topf A, Jirak P, Fiedler L, Granitz C, Van Almsick V, Semo D, Zagidullin N, Dieplinger AM, Sindermann J, Reinecke H, Hoppe UC, Pistulli R, Motloch LJ
  Effects of Angiotensin Receptor-Neprilysin Inhibitors (ARNIs) on the Glucose and Fat Metabolism Biomarkers Leptin and Fructosamine.
  J Clin Med. 2023 12(9):3083. DOI: 10.3390/jcm12093083.

• Boxhammer E, Bellamine M, Szendey I, Foresti M, Bonsels M, Kletzer J, Jirak P, Topf A, Kraus J, Fiedler L, Dieplinger AM, Hoppe UC, Strohmer B, Eckardt L, Pistulli R, Motloch LJ, Larbig R
  Impact of cavotricuspid isthmus ablation for typical atrial flutter and heart failure in the elderly-results of a retrospective multi-center study.
  Front Cardiovasc Med. 2023 10:1109404. DOI: 10.3389/fcvm.2023.1109404

• Fiedler L, Motloch LJ, Jirak P, Gumerov R, Davtyan P, Gareeva D, Lakman I, Tataurov A, Lasinova G, Pavlov V, Hauptmann L, Kopp K, Hoppe UC, Lichtenauer M, Pistulli R, Dieplinger AM, Zagidullin N
  Investigation of hs-TnI and sST-2 as Potential Predictors of Long-Term Cardiovascular Risk in Patients with Survived Hospitalization for COVID-19
  Front Cardiovasc Med. 2022 10;10(11):2889. DOI: 10.3390/biomedicines10112889.

• Motloch LJ, Jirak P, Moritz M, Fiedler L, Davtyan PA, Lakman IA, Gareeva DF, Tyurin A, Gumerov RM, Matskeplishvili ST, Pavlov V, Cai B, Kopp K, Topf A, Hoppe UC, Pistulli R, Zagidullin N
  Early antithrombotic post-discharge therapy using prophylactic DOAC or dipyridamole improves long-term survival and cardiovascular outcomes in hospitalized COVID-19 survivors.
  Front Cardiovasc Med. 2022 29;9:916156. DOI: 10.3389/fcvm.2022.916156

• Motloch LJ, Jirak P, Gareeva D, Davtyan P, Gumerov R, Lakman I, Tataurov A, Zulkarneev R, Kabirov I, Cai B, Valeev B, Pavlov V, Kopp K, Hoppe UC, Lichtenauer M, Fiedler L, Pistulli R, Zagidullin N.
  Cardiovascular Biomarkers for Prediction of in-hospital and 1-Year Post-discharge Mortality in Patients With COVID-19 Pneumonia.
  Front Med (Lausanne). 2022 28;9:906665. DOI: 10.3389/fmed.2022.906665.

• Jirak P, Mirna M, Van Almsick V, Shomanova Z, Mahringer M, Lichtenauer M, Kopp K, Topf A, Sieg F, Kraus J, Gharibeh SX, Hoppe UC, Fiedler L, Larbig R, Pistulli R, Motloch LJ, Dieplinger AM.
  Gender-Specific Differences in the Intensive Care Treatment of COVID-19 Patients.
  J Pers Med. 2022 23;12(5):849. DOI: 10.3390/jpm12050849.

• Topf A, Mirna M, Paar V, Motloch LJ, Bacher N, Franz M, Hoppe UC, Kretzschmar D, Lichtenauer M.
  Differential Diagnosis between Takotsubo Syndrome and Acute Coronary Syndrome-A Prospective Analysis of Novel Cardiovascular Biomarkers for a More Selective Triage.
  J Clin Med. 2022 25;11(11):2974. DOI: 10.3390/jcm11112974

• Jirak P, Van Almsick V, Dimitroulis, D, Mirna M, Seelmaier C, Shomanova Z, Wernly B, Semo D, Dankl D, Mahringer M, Lichtenauer M, Hoppe UC, Reinecke H, Pistulli R, Larbig R, Motloch LJ.
  Dexamethasone improves cardiovascular outcomes in critically ill COVID-19, a real world scenario multicenter analysis. Front Med.
  Front Med (Lausanne). 2022;9:808221. DOI: 10.3389/fmed.2022.808221

• Topf A, Mirna M, Paar V, Motloch LJ, Grueninger J, Dienhart C, Schulze PC, Brandt MC, Larbig R, Hoppe UC, Kretzschmar D, Lichtenauer M.
  The differential diagnostic value of selected cardiovascular biomarkers in Takotsubo syndrome.
  Clin Res Cardiol. 2022;111(2):197-206. DOI: 10.1007/s00392-021-01956-2.

• Topf A, Mirna M, Dienhart C, Jirak P, Bacher N, Boxhammer E, Gharibeh SX, Motloch LJ, Hoppe UC, Lichtenauer M.
  Pretreatment with Betablockers, a Potential Predictor of Adverse Cardiovascular Events in Takotsubo Syndrome.
  Biomedicines. 2022;10(2):464. DOI: 10.3390/biomedicines10020464.

• Jirak P, Haertel F, Mirna M, Rezar R, Lichtenauer M, Paar V, Motloch LJ, Topf A, Yilmaz A, Hoppe UC, Schulze PC, Nuding S, Werdan K, Kretzschmar D, Pistulli R, Ebelt H.A Comparative Analysis of
  Novel Biomarkers in Sepsis and Cardiovascular Disease.
  Appl. Sci. 2022;12(3), 1419; DOI: 10.3390/app12031419

• Jirak P, Shomanova Z, Larbig R, Dankl D, Frank N, Seelmaier C, Butkiene D, Lichtenauer M, Mirna M, Strohmer B, Sackarnd J, Hoppe UC, Sindermann J, Reinecke H, Frommeyer G, Motloch LJ,
  Pistulli R.
  Higher Incidence of Stroke in Severe COVID-19 Is Not Associated With a Higher Burden of Arrhythmias: Comparison With Other Types of Severe Pneumonia.
  Front Cardiovasc Med. 2021;8:763827. DOI: 10.3389/fcvm.2021.763827.

• Zagidullin, NS, Motloch, LJ, Musin, TI, Bagmanova, ZA, Lakman, IA, Tyurin, AV, Gumerov, RM, Enikeev, D, Cai, B, Gareeva, DF, Davtyan, PA, Gareev, DA, Talipova, HM, Badykov, MR, Jirak, P, Kopp, K, Hoppe, UC, Pistulli, R, Pavlov, V.
  J-waves in acute COVID-19: A novel disease characteristic and predictor of mortality?
  PLoS One. 2021;16(10):e0257982. DOI: 10.1371/journal.pone.0257982.

• Topf A, Mirna M, Bacher N, Paar V, Motloch LJ, Ohnewein B, Larbig R, Grueninger J, Hoppe UC, Lichtenauer M, Pistulli R.
  Analysis of Selected Cardiovascular Biomarkers in Takotsubo Cardiomyopathy and the Most Frequent Cardiomyopathies.
  Front Cardiovasc Med. 2021;8:700169. DOI: 10.3389/fcvm.2021.700169

• Topf A, Mirna M, Bacher N, Paar V, Edlinger C, Motloch LJ, Gharibeh S, Bannehr M, Hoppe UC, Lichtenauer M.
  The Value of Fetuin-A as a Predictor to Identify Takotsubo Patients at Risk of Cardiovascular Events.
  J Cardiovasc Dev Dis. 202;8(10):127. DOI: 10.3390/jcdd8100127.

• Schernthaner C, Topf A, Motloch LJ, Kraus J, Hauptmann L, Hoppe UC, Strohmer B
  Case report: Short-long-short mechanism triggering sustained ventricular tachycardia in a patient with a single-chamber ICD but inhibiting antitachycardia therapy.
  Front Cardiovasc Med. 2022 9:984262. DOI: 10.3389/fcvm.2022.984262

• Jirak P, Mirna M, Rezar R, Motloch LJ, Lichtenauer M, Jordan J, Binneboessel S, Tank J, Limper U, Jung C.
  How spaceflight challenges human cardiovascular health.
  Eur J Prev Cardiol. 2022 11:zwac029. DOI: 10.1093/eurjpc/zwac029

• Mirna M, Holnthoner M, Topf A, Jirak P, Fejzic D, Paar V, Kellermair J, Blessberger H, Reiter C, Kammler J, Motloch LJ, Jung C, Kretzschmar D, Franz M, Alushi B, Lauten A, Hoppe UC, Steinwender C, Lichtenauer M.
  Tumor necrosis factor alpha-an underestimated risk predictor in patients undergoing transcatheter aortic valve replacement (TAVR)?
  J Clin Lab Anal. 2021;35(11):e23977. DOI: 10.1002/jcla.23977.

• Jirak P, Larbig R, Shomanova Z, Fröb EJ, Dankl D, Torgersen C, Frank N, Mahringer M, Butkiene D, Haake H, Salzer HJF, Tschoellitsch T, Lichtenauer M, Egle A, Lamprecht B, Reinecke H, Hoppe UC, Pistulli R, Motloch LJ.
  Myocardial injury in severe COVID-19 is similar to pneumonias of other origin: results from a multicentre study. 
  ESC Heart Fail. 2021;8(1):37-46. doi: 10.1002/ehf2.13136.

• Topf A, Paar V, Grueninger J, Wernly B, Kopp K, Weber T, Schernthaner C, Mirna M, Gharibeh SX, Larbig R, Pistulli R, Hoppe UC, Lichtenauer M, Motloch LJ, Brandt MC
  sST2 Predicts Short Term Therapy Success in Patients with Therapy Resistant Hypertension after Renal Sympathetic Denervation
  Appl. Sci. 2021; 11(23), 11130; DOI: 10.3390/app112311130

• Abdullah KQA, Roedler JV, Vom Dahl J, Szendey I, Dimitroulis D, Eckardt L, Topf A, Ohnewein B, Fritsch L, Föttinger F, Brandt MC, Wernly B, Motloch LJ, Larbig R.
  Cardiac Arrhythmias in Survivors of Sudden Cardiac Death Requiring Impella Assist Device Therapy. 
  J Clin Med. 2021; 10(7):1393. doi: 10.3390/jcm10071393

• Abdullah KQA, Roedler JV, Vom Dahl J, Szendey I, Haake H, Eckardt L, Topf A, Ohnewein B, Jirak P, Motloch LJ, Wernly B, Larbig R.
  Impella use in real-world cardiogenic shock patients: Sobering outcomes. 
  PLoS One. 2021;16(2):e0247667. doi: 10.1371/journal.pone.0247667. eCollection 2021.

• Mirna M, Lauten A, Jirak P, Rezar R, Wernly B, Paar V, Felder TK, Hoppe UC, Motloch LJ, Jung C, Alushi B, Lichtenauer M, Salmhofer H.
  Serum levels of C-terminal FGF23 (cFGF23) are associated with 1-year-mortality in patients undergoing transcatheter aortic valve replacement (TAVR)
  Eur J Intern Med. 2021; 85:98-107. DOI: 10.1016/j.ejim.2020.09.022

• Topf A, Bacher N, Kopp K, Mirna M, Larbig R, Brandt MC, Kraus J, Hoppe UC, Motloch LJ, Lichtenauer M.
  Management of Implantable Cardioverter-Defibrillators during Pregnancy-A Systematic Review. 
  J Clin Med. 2021;10(8):1675. doi: 10.3390/jcm10081675.

• Topf A, Pleininger T, Motloch LJ, Mirna M, Kopp K, Lichtenauer M, Hoppe UC, Salmhofer H.
  Subcutaneous administration of levothyroxine: a novel approach to refractory hypothyroidism - A review and a case report. 
  Arch Endocrinol Metab. 2021; 2359-3997000000349. doi: 10.20945/2359-3997000000349.

• Strohmer B, Danmayr F, Kraus J, Motloch LJ, Hoppe, UC.
  Rare Variant of a Pre-excitation Syndrome - electrophysiological Risk Stratification and Differential Diagnosis.
  J KARDIOL. 2021; 28(5-6): 182-187.

• Jirak P, Pistulli R, Lichtenauer M, Wernly B, Paar V, Motloch LJ, Rezar R, Jung C, Hoppe UC, Schulze PC, Kretzschmar D, Braun-Dullaeus RC, Bekfani T
  Expression of the Novel Cardiac Biomarkers sST2, GDF-15, suPAR, and H-FABP in HFpEF Patients Compared to ICM, DCM, and Controls.
  J Clin Med 2020, 15;9(4):1130 DOI: 10.3390/jcm9041130

• Zagidullin N, Motloch LJ, Gareeva D, Hamitova A, Lakman I, Krion I, Popov D, Zulkarneev R, Paar V, Kopp K, Jirak P, Ishmetov V, Tulbaev E, Hoppe UC, Pavlov V
  Combining Novel Biomarkers for Risk Stratification of Two-Year Cardiovascular Mortality in Patients with ST-Elevation Myocardial Infarction
  J Clin Med 2020, 18;9(2):550 DOI: 10.3390/jcm9020550

• Wernly B, Paar V, Aigner A, Pilz PM, Podesser BK, Förster M, Jung C, Hofbauer JP, Tockner B, Wimmer M, Kraus T, Motloch LJ, Hackl M, Hoppe UC, Kiss A, Lichtenauer M
  Anti-CD3 Antibody Treatment Reduces Scar Formation in a Rat Model of Myocardial Infarction.
  Cells 2020, 25;9(2). pii: E295 DOI: 10.3390/cells9020295

• Topf A, Mirna M, Ohnewein B, Jirak P, Kopp K, Fejzic D, Haslinger M, Motloch LJ, Hoppe UC, Berezin A, Lichtenauer M.
  The Diagnostic and Therapeutic Value of Multimarker Analysis in Heart Failure. An Approach to Biomarker-Targeted Therapy. 
  Front Cardiovasc Med. 2020; 7:579567. doi: 10.3389/fcvm.2020.579567. eCollection 2020.

• Kopp K, Lichtenauer M, Motloch LJ, Hoppe UC, Egle A, Salzer HJF, Lamprecht B, Tomasits J, Müller HM, Dieplinger A.
  Interdisciplinary Model for Scheduling Post-discharge Cardiopulmonary Care of Patients Following Severe and Critical SARS-CoV-2 (Coronavirus) Infection.
  Front Cardiovasc Med. 2020 A14;7:157. DOI: 10.3389/fcvm.2020.00157v

• Shomanova Z, Ohnewein B, Schernthaner C, Höfer K, Pogoda C, Frommeyer G, Wernly B, Brandt MC, Dieplinger AM, Reinecke H, Hoppe UC, Strohmer B, Pistulli R, Motloch LJ
  Classic and Novel Biomarkers as Potential Predictors of Ventricular Arrhythmias and Sudden Cardiac.
  J Clin Med, 2020, 15;9(4):1130 DOI: 10.3390/jcm9020578

• Topf A, Motloch LJ, Kraus J, Danmayr F, Mirna M, Schernthaner C, Hoppe UC, Strohmer B
  Exercise-related T-wave oversensing: an underestimated cause of reduced exercise capacity in a pacemaker-dependent patient-a case report and review of the literature.
  J Interv Card Electrophysiol. 2020 DOI: 10.1007/s10840-019-00698-6

• Edlinger C, Paar V, Tuscher T, Jirak P, Motloch LJ, Kammler J, Blessberger H, Kraus J, Hoppe UC, Steinwender C, Kypta A, Lichtenauer M
  Potential mechanisms of endothelialisation in individuals implanted with a leadless pacemaker systems: An experimental in vitro study.
  J Electrocardiol. 2019; [Epub ahead of print] DOI: 10.1016/j.jelectrocard.2019.04.012

• Nass RD, Motloch LJ, Paar V, Lichtenauer M, Baumann J, Zur B, Hoppe UC, Holdenrieder S, Elger CE, Surges R
  Blood markers of cardiac stress after generalized convulsive seizures.
  Epilepsia 2019; 60(2):201-210 DOI: 10.1111/epi.14637

• Granitz M, Motloch LJ, Granitz C, Meissnitzer M, Hitzl W, Hergan K, Schlattau A
  Comparison of native myocardial T1 and T2 mapping at 1.5T and 3T in healthy volunteers: Reference values and clinical implications. Wien Klin Wochenschr. 2019; 131(7-8):143-155 DOI: 10.1007/s00508-018-1411-3

• Jirak P, Motloch LJ, Granitz C
  [COVID-19: Impact on the cardiovascular system.]
  Universum Innere Medizin. 08/2019

• Paar V, Jirak P, Larbig R, Zagidullin NS, Brandt MC, Lichtenauer M, Hoppe UC, Motloch LJ
  Pathophysiology of Calcium Mediated Ventricular Arrhythmias and Novel Therapeutic Options with Focus on Gene Therapy.
  Int J Mol Sci. 2019 Oct 24;20(21). pii: E5304 DOI: 10.3390/ijms20215304

• Motloch LJ, Cacheaux M, Ishikawa K, Xie C, Hu J, Aguero J, Fish KM, Hajjar RJ, Akar FG
  Primary effect of SERCA2a gene transfer on conduction reserve in chronic myocardial infarction.
  J Am Heart Assoc. 2018; 7(18):e009598 DOI: 10.1161/JAHA.118.009598

• Larbig R, Motloch LJ (equally contributed), Bettin M, Fischer A, Bode N, Frommeyer G, Loeher A, Köbe J, Reinke F, Eckardt L
  Device-updates successfully reduce T-Wave Oversensing and inappropriate Shocks in S-ICD Patients.
  Neth Heart J. 2018; 26(12):606-611 DOI: 10.1007/s12471-018-1160-y

• Larbig R, Motloch LJ (equally contributed), Bettin M, Fischer A, Frommeyer G, Reinke F, Loeher A, Eckardt L, Köbe J
  Postoperative ergometry guided programming does not prevent T-Wave oversensing and inappropriate shocks in S-ICD patients.
  Pacing Clin Electrophysiol. 2018; 41(6):567-571 DOI: 10.1111/pace.13327

• Paar V, Jirak P, Larbig R, Zagidullin NS, Brandt MC, Lichtenauer M, Hoppe UC, Motloch LJ
  Pathophysiology of Calcium Mediated Ventricular Arrhythmias and Novel Therapeutic Options with Focus on Gene Therapy.
  Int J Mol Sci. 2019 Oct 24;20(21). pii: E5304 DOI: 10.3390/ijms20215304

• Watanabe S, Ishikawa K, Fish K, Oh JG, Motloch LJ, Kohlbrenner E, Lee P, Xie C, Lee A, Liang L, Kho C, Leonardson L, McIntyre M, Wilson S, Samulski RJ, Kranias EG, Weber T, Akar FG, Hajjar RJ
  Protein phosphatase inhibitor-1 gene therapy in a swine model of nonischemic heart failure.
  J Am Coll Cardiol. 2017; 70(14):1744-1756 DOI: 10.1016/j.jacc.2017.08.013

• Motloch LJ, Ishikawa K, Xie C, Hu J, Aguero J, Fish KM, Hajjar RJ, Akar FG
  Increased afterload following myocardial infarction promotes conduction-dependent arrhythmias that are unmasked by hypokalemia.
  JACC Basic Transl Sci. 2017; 2(3):258-269 DOI: 10.1016/j.jacbts.2017.02.002

• Motloch LJ, Larbig R, Reda S, Darabi T, Motloch KA, Wernly B, Lichtenauer M, Gebing T, Schwaiger A, Zagidullin N, Wolny M, Hoppe UC
  Long QT syndrome associated caveolin-3 mutations differentially regulate the hyperpolarization-activated cyclic nucleotide gated channel 4.
  Physiol Int. 2017; 104(2):130-138 DOI: 10.1556/2060.104.2017.2.6

• Wernly B, Gonçalves I, Kiss A, Paar V, Mösenlechner T, Leisch M, Santer D, Motloch LJ, Klein KU, Tretter EV, Kretzschmar D, Podesser B, Jung C, Hoppe UC, Lichtenauer M
  Differences in stem cell processing lead to distinct secretomes secretion-implications for differential results of previous clinical trials of stem cell therapy for myocardial infarction.
  Biotechnol J. 2017; 12(9) DOI: 10.1002/biot.201600732

• Lichtenauer M, Jirak P, Wernly B, Paar V, Rohm I, Jung C, Schernthaner C, Kraus J, Motloch LJ, Yilmaz A, Hoppe UC, Christian Schulz   e P, Kretzschmar D, Pistulli R
  A comparative analysis of novel cardiovascular biomarkers in patients with chronic heart failure.
  Eur J Intern Med. 2017; 44:31-38 DOI: 10.1016/j.ejim.2017.05.027

• Larbig R, Reda S, Paar V, Trost A, Leitner J, Weichselbaumer S, Motloch KA, Wernly B, Arrer A, Strauss B, Lichtenauer M, Reitsamer HA, Eckardt L, Seebohm G, Hoppe UC, Motloch LJ
  Through modulation of cardiac Ca2+-handling, UCP2 affects cardiac electrophysiology and influences the susceptibility for Ca2+-mediated arrhythmias.
  Experiment Physiol. 2017; 102(6):650-662 DOI: 10.1113/EP086209

• Motloch LJ, Reda S, Larbig R, Wolff A, Motloch KA, Wernly B, Granitz C, Lichtenauer M, Wolny M, Hoppe UC
  Characteristics of coronary artery disease among patients with atrial fibrillation compared to patients with sinus rhythm.
  Hellenic J Cardiol. 2017; S1109-9666(16)30160-9 9  DOI: 10.1016/j.hjc.2017.03.001

• Motloch LJ, Gebing T, Reda S, Schwaiger A, Wolny M, Hoppe UC
  UCP3 regulates single-channel activity of the cardiac mCa1.
  J Membr Biol. 2016; 249(4):577-84. DOI: 10.1007/s00232-016-9913-2

• Motloch LJ, Larbig R, Gebing T, Reda S, Schwaiger A, Leitner J, Wolny M, Eckardt L, Hoppe UC
  By regulating mitochondrial Ca2+-Uptake UCP2 modulates intracellular Ca2.
  PLoS One. 2016; 11(2):e0148359. DOI: 10.1371/journal.pone.0148359

• Xie C, Hu J, Motloch LJ, Karam BS, Akar FG
  The classically cardioprotective agent diazoxide elicits arrhythmias in type 2 diabetes mellitus.
  J Am Coll Cardiol. 2015; 66(10):1144-56. DOI: 10.1016/j.jacc.2015.06.1329.
• Motloch LJ, Reda S, Wolny M, Hoppe UC
  UCP2 modulates cardioprotective effects of Ru360 in isolated cardiomyocytes during Ischemia.
  Pharmaceuticals (Basel). 2015; 8(3):474-82. DOI: 10.3390/ph8030474.
• Motloch LJ, Hu J, Akar FG
  The mitochondrial translocator protein and arrhythmogenesis in ischemic heart disease.
  Oxid Med Cell Longev. 2015; 2015:234104. DOI:10.1155/2015/234104.
• Motloch LJ, Akar FG
  Gene therapy to restore electrophysiological function in heart failure.
  Expert Opin Biol Ther. 2015; 15(6):803-17. DOI:10.1517/14712598.2015.1036734.
• Rottlaender D, Motloch LJ (equally contributed), Schmidt D, Reda S, Larbig R, Wolny M, Dumitrescu D, Rosenkranz S, Erdmann E, Hoppe UC
  Clinical impact of atrial fibrillation in patients with pulmonary hypertension.
  PLoS One. 2012; 7:e33902. doi: 10.1371/journal.pone.0033902.

• Motloch LJ, Reda S, Rottlaender D, Khatib R, Müller-Ehmsen J, Seck C, Strauch J, Madershahian N, Erdmann E, Wahlers T, Hoppe UC
  Postprocedural atrial fibrillation after transcatheter aortic valve implantation versus surgical aortic valve replacement.
  Ann Thorac Surg. 2012; 93:124-31. DOI: 10.1016/j.athoracsur.2011.08.078.

• Motloch LJ, Rottlaender D, Reda S, Larbig R, Bruns M, Müller-Ehmsen J, Strauch J, Madershahian N, Erdmann E, Wahlers T, Hoppe UC
  Local versus general anesthesia for transfemoral aortic valve implantation.
  Clin Res Cardiol. 2012; 101:45-53. DOI: 10.1007/s00392-011-0362-8.

• Motloch LJ, Reda S, Rottlaender D, Heigert M, Hoppe UC
  Transcatheter aortic valve replacement: when should it be used in aortic stenosis?
  Wien Med Wochenschr. 2012; 162:340-8. DOI: 10.1007/s10354-012-0136-6.

• Rottlaender D, Motloch LJ, Reda S, Larbig R, Hoppe UC
  Cardiac arrest due to long QT syndrome associated with excessive consumption of energy drinks.
  Int J Cardiol. 2012; 158:e51-2. DOI: 10.1016/j.ijcard.2011.10.017.

• Reda S, Motloch LJ, Hoppe UC
  Heart failure with preserved ejection fraction.
  Kardiologe. 2011; 5:237-44.

• Reda S, Motloch LJ, Hoppe UC
  Heart failure with preserved ejection fraction.
  Kardiologe. 2011; 5:237-44.

• Motloch LJ, Rottlaender D, Darabi T, Joost I, Erdmann E, Hoppe UC
  Conservative management of Candida infection of prosthetic aortic graft by means of caspofungin and fluconazole alone.
  2011; 38:197-200.

• Brandt MC, Endres-Becker J, Zagidullin N, Motloch LJ, Er F, Rottlaender D, Michels G, Herzig, S, Hoppe UC
  Effects of KCNE2 on HCN isoforms: distinct modulation of membrane expression and single channel properties.
  Am J Physiol Heart Circ Physiol. 2009; 297(1):H355-63. DOI: 10.1152/ajpheart.00154.2009.

• Steinwender C, Hartenthaler B, Lambert T, Kypta A, Kammler J, Hönig S, Hofmann R, Kerschner K, Leisch F
  Incidence of stent thrombosis in patients with drug eluting stents and short-term dual antiplatelet therapy.
  EuroIntervention. 2009 Mar;4(5):593-9. doi: 10.4244/eijv4i5a100.

• Steinwender C, Hofmann R, Hartenthaler B, Leisch F
  Resolution of a coronary embolus by intravenous application of bivalirudin.
  Int J Cardiol. 2009 Mar 6;132(3):e115-6. doi: 10.1016/j.ijcard.2007.08.032.

• Rottlaender D, Motloch LJ, Hoppe UC
  Cryothermal energy: a new perspective for interventional therapy of cardiac arrhythmias?
  Dtsch Med Wochenschr. 2009; 134(43):2174-8. DOI: 10.1055/s-0029-1241926.